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NIEHS/EPA Metals - Bioavailability
Internet-based seminar
Hosted by U.S. EPA/OSRTI & NIEHS Superfund Basic Research Program

This is the first in a series of three seminars on Metals sponsored by the EPA Technology Innovation Office and the NIEHS Superfund Basic Research Program. This event will highlight recent advances in assessing and limiting the bioavailability of metal contaminants. Dr. Joseph Graziano, of Columbia University, will discuss his team's current research into phosphate treatment of lead (Pb)-contaminated soils. Adding phosphate amendments to soil has been shown to dramatically reduce the absorption of Pb in humans. For example, Pb absorption from a contaminated soil obtained from a former smelter site in Joplin, Missouri, averaged 36% among a group of adult volunteers. However, Pb absorption from an adjacent soil that had been "fertilized" in the field 18 months earlier averaged only 15%. This 57% reduction in Pb bioavailability implies that the Pb hazard at many Superfund sites can be substantially reduced in a very cost effective manner. Dr. James Shine, of Harvard University, is developing a sampling device that can measure the free metal ion concentration of many metals at the same time. The sampler, called the "Gellyfish," functions through the equilibration of immobilized ligands (held in polyacrylamide gel) with the free metal ion concentration in the surrounding solution. This sampler can measure the free metal ion concentration of many metals at the same time. Knowledge of the free metal ion concentration is a critical determinant for understanding metal speciation, and thus understanding the environmental mobility and bioavailability of metals in aquatic ecosystems. This new analytical technique is ready to be demonstrated in a pilot scale application. For general information contact Larry Whitson by telephone at 919-806-4244
More information on this event is available, click here This link opens in a new window.

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Archives of past CLU-IN internet seminars are available in the CLU-IN Studio at You will be able to view the slide and hear an audio stream of the presentation as it occurred.Image denoting link exits Trainex system

Previous Events (click to view/hide)
Bullet  Live Online Class, Internet Based
  April 9, 2003 - April 9, 2003
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